One study done by Luther Fry at his own clinic monitored patients with one eye implanted with an aspheric lens and the other not., has also had patients implanted with a standard IOL in one eye and an aspheric lens in the other eye."My experience suggests that if the refractive error is plano or very close to plano in both eyes, or if the patient has enough residual refractive error that he or she chooses to wear spectacle correction, then the patient will notice a difference in terms of color, clarity and brightness, favoring the aspheric lens," he says.
"The power of the implant also matters; if a hyperopic patient requires a 30 D implant, a standard lens would induce far more positive spherical aberration than the 10 D implant a myope might require."Wavefront analysis usually shows some differences between the lenses," he says."But one recent study found that if you don't preselect the patients—if they're randomized, with a different aspheric lens in each eye—most patients don't express a strong preference for any of three lenses.Centration is another concern that is more of an issue with some aspheric lenses.Standard IOLs, which add positive spherical aberration to the optical system, do not create major problems if they decenter.